What is PDRN?
PDRN (Polydeoxyribonucleotide) is a regenerative ingredient derived from salmon DNA often called “salmon sperm” in aesthetics. It’s known for its incredible healing, anti-inflammatory and skin-repairing properties.
When applied to the skin, PDRN helps your body produce new collagen, repair damaged tissue and increase hydration, leaving your complexion smoother, firmer and more radiant.
At Spa Medicca, we use Salmon Sperm (PDRN), a premium formula that combines:
Copper Tripeptide — enhances healing and collagen production
PDRN from salmon DNA — regenerates and strengthens skin
Glutathione — brightens dull skin and evens tone while protecting against signs of aging
This unique blend deeply hydrates, calms inflammation, and improves texture for that healthy, glowing finish our patients love.
PDRN can be added to many of your favorite treatments, including:
PDRN with Microneedling
Pairing PDRN with microneedling creates a powerful skin-renewing combination that enhances both collagen stimulation and recovery.
Microneedling creates tiny micro-channels in the skin, allowing the PDRN solution to absorb deeply and work at a cellular level for more visible rejuvenation.
Benefits:
Enhanced absorption: Micro-channels allow PDRN to penetrate the dermis where it can accelerate repair and renewal.
Boosted collagen & elasticity: Works synergistically with microneedling to smooth fine lines and improve firmness.
Faster healing: Calms redness, reduces downtime and speeds post-treatment recovery.
Improved texture & tone: Refines pores, softens acne scars and brightens dull skin.
Hydrated glow: Leaves skin plump, radiant and refreshed from within.
Ideal for patients wanting overall skin rejuvenation. This pairing delivers smoother, firmer and more luminous results.
PDRN with Dermaplaning
Combining PDRN with dermaplaning takes exfoliation and hydration to the next level.
Dermaplaning gently removes dead skin cells and fine vellus hair, allowing PDRN to soak directly into fresh, receptive skin for amplified nourishment and glow.
Benefits:
Deeper penetration: Freshly exfoliated skin maximizes PDRN absorption for better healing and repair.
Enhanced radiance: Instantly brightens dull complexions and smooths skin texture.
Hydration boost: PDRN deeply moisturizes, leaving skin soft and dewy.
Calms and soothes: Reduces redness and supports healthy barrier recovery post-exfoliation.
Perfect prep: Ideal before events or as a maintenance glow treatment to keep skin healthy year-round.
This combination is perfect for anyone seeking a smoother, softer and instantly glowing complexion.
Your provider will recommend the best method based on your goals and treatment plan.
After your session, skin may look slightly pink for a short time, then quickly becomes hydrated, radiant, and smoother. Results continue to improve as collagen production increases in the following weeks.
Anyone looking to:
Speed up post-treatment healing
Improve skin texture and elasticity
Restore hydration and glow
Support overall skin regeneration
Whether added to microneedling or dermaplaning appointment, PDRN helps you get the most out of every treatment.
Give your skin a powerful boost before any holidays, special occasion or when your skin is needing some extra love. Click the link below to book an appointment!
Disclaimer: This content is for informational and cosmetic purposes only. Your Spa Medicca provider will evaluate your skin and medical history to determine if PDRN is right for you.